WebCHIP28 has been proposed to be the major water channel in these and other tissues (Agre et al., 1993). The deduced amino acid sequence of CHIP28 contains 4 cysteines, and the proposed membrane topology includes six probable bilayer-spanning domains (Preston and Agre, 1991). Moreover, the N- and C-terminal halves of the CHIP28 ... WebIn 1993 CHIP28 was renamed aquaporin 1. Looking in retrospect, asking the crucial question, when was the first water channel protein, aquaporin 1, discovered, a fair and clear cut answer would be: the first water channel protein, now called aquaporin 1, was identified or "seen" in situ in the human RBC membrane by Benga and coworkers in 1986.
CHIPS - Definition by AcronymAttic
WebJan 2, 1993 · CHIP28 is a 28-kD integral protein which was proposed to mediate transmembrane water movement in red cells and kidney (Preston, G. M., T. P. Carroll, W. B. Guggino, and P. Agre. 1992. Science [Wash. DC]. 256:385-387). To determine whether CHIP28 could account for renal epithelial water transport, we used specific polyclonal … Webidentification of this protein, so-called “CHIP28,” as a water channel has led to the discovery of a large family of water channels and related proteins (reviewed in Ref. 7). This family was first named the MIP family (MIP proteins) as an acronym for the first cloned protein of this family, the major how many eggs can fleas lay per day
CHIP28 water channels are localized in constitutively water …
WebJan 15, 1993 · CHIP28 is a 28-kD integral protein which was proposed to mediate transmembrane water movement in red cells and kidney (Preston, G. M., T. P. Carroll, … WebAug 25, 1992 · Purified CHIP28 from human RBCs was reconstituted into proteoliposomes in order to establish if CHIP28 is itself the functional unit of water channels and to characterize its physiological behavior. CHIP28 proteoliposomes exhibit Pf which is up to 50-fold above that of control liposomes, but permeability to urea and protons is not increased. WebCHIP28) encodes a single tandem repeat of two CHIP28 subunits. Tu prepare cDNAS encoding CHIP28 trimers (and then tetramers), the procedure was repeated using the digested PCR fragment and NcoI- ... The abbreviations used are: PCR, polymerase chain reaction; PBS, phosphate-buffered saline; WT, wild-type; RRL, rabbit reticulocyte ly- high times texas